Endocrine Abstracts

Diagnosis of Cushing’s disease can be a difficult and lengthy process with repeated and dynamic testing required to ensure the correct diagnosis is made prior to invasive intervention such as surgery. This case demonstrates that even with meticulous investigation the underlying cause of the disease can still be evasive. A 43-year-old female presented with a history of hypertension since age 20, managed with Amlodipine (10 mg) and Ramipril (10 mg). She was investigated for...

Background: Carcinoid Heart Disease (CHD) is a well-documented but devastating complication of metastatic neuroendocrine tumours (mNETs). Occurring in approximately 20% of patients with Carcinoid Syndrome (CS) the prognosis is poor, with a 3-year survival of 31% versus 68% in patients with mNETs without CHD1. Management of these patients requires a multidisciplinary approach to manage tumour load via medical and/or surgical options, alongside contro...